HPV Watch

“HPV Watch” is a section of the Clearinghouse that houses a range of information, publications, guidance documents and media stories on vaccines which prevent cervical cancer. These vaccines work by protecting women against infection with the types of humanpapilloma virus that are associated with the majority of cervical cancer cases worldwide.

The first vaccine of this kind, Gardasil, manufactured by Merck was approved by the US Food and Drug Administration in June 2006. Another vaccine is currently being developed by GlaxoSmithKline and is expected to be approved in 2007.

The greatest burden of cervical cancer is among women and girls in the developing world, who have limited or no access to screening and treatment programs. Introducing HPV vaccine as part of programs that provide screening, treatment and potentially a range of other sexual and reproductive health and HIV-related services could have a profound impact on the health and well-being of young girls, adolescents and women worldwide.

This resource contains tools for many stakeholders, working in many different fields including HIV/AIDS, cancer prevention and sexual and reproductive health. Working together, a broad coalition can help secure access to this important vaccine and lay the foundation for introduction of future products like AIDS vaccines, microbicides and other new technologies.

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What's New - Basics - Useful Links - Journal Articles - Meeting Reports - News
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What's New

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Support the Global Call to Stop Cervical Cancer

Available online in multiple languages, the Global Call urges governments, agencies, donors, medical professionals, industry and civil society to do their respective parts in ensuring universal access to HPV vaccines and cervical cancer screening and treatment.

AVAC urges you to sign on to the Call!

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• "GSK To Begin Trial Comparing its Experimental HPV Vaccine Cervarix to Merck's Gardasil" - Kaiser Network Update - January 19, 2007
• Stop Cervical Cancer: Accelerating Global Access to HPV Vaccines - London, December 12-13, 2006
  - Advocacy, Information and Communication: Engaging Stakeholders at All Levels to Prepare for the Introduction of HPV Vaccines, Fisher and Bass
  - HPV Vaccines: Cost and Financing, Saxenian and Hecht
  - HPV Vaccines: Regulatory Issues, Brooke and Sherris
  - Assuring Access to Vaccines that Prevent Cervical Cancer, Pollack

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The Basics

• Outlook. Preventing cervical cancer: unprecedented opportunities for improving women's health (2007) - This 12-page paper summarizes key information about HPV and cervical cancer, the state of cervical cancer screening and treatment, and the role of vaccination in cancer prevention. (Available for download in additional languages here.)
• HPV Vaccine Fact Sheet from the Kaiser Family Foundation
• Ask the Experts: HPV Vaccine - A panel of experts address the implementation of the new vaccine against human papillomavirus (HPV) - January 10, 2007
• Preparing for the Introduction of HPV vaccines: policy and programme guidance for countries, WHO, 2006
• The Emerging Adolescent Agenda: HPV Vaccine, AIDS Prevention Research, and the New Opportunities for Reaching the Young People of the World, from the 2006 AVAC Report, AIDS Vaccines: The Next Frontiers

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Useful Links

• RHO Cervical Cancer -- The RHO website has featured information on cervical cancer prevention for over ten years. RHO Cervical Cancer represents a dramatic expansion of the site, with the addition of a vast library of technical documents, training materials, patient education websites, and films and animation from world leaders in the field, such as the WHO, the US Centers for Disease Control and Prevention, PATH, and many others.
• Partnership to End Cervical Cancer -- The Partnership to End Cervical Cancer is a Glaxo SmithKline-supported broad-based coalition of more than 20 established organizations with the resources and expertise to reach women throughout the United States. Participating organizations comprise medical and public health experts with the ability to affect public health behavior and policy change.
• PATH cervical cancer vaccine webpage -- Get basic
  information and fact sheets as well as some detail on PATH programs
  introducing HPV vaccine in developing countries

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Journal Articles

• A semi-qualitative study of attitudes to vaccinating adolescents against human papillomavirus without parental consent - BMC Public Health, February 2007
• Epidemiology of HPV 16 and Cervical Cancer in Finland and the Potential Impact of Vaccination: Mathematical Modelling Analysis, Barnabas et. al. - PLoS Medicine, May 2006
• HPV Vaccination: Predicting Its Effect on Cervical Cancer Rates, Barnabas et. al. PLoS Medicine, May 2006
• Education, training and communication for HPV vaccines, Sherris et. al. - Vaccine, 2006
• Who should be vaccinated against human papillomavirus? The Lancet Infectious Diseases, January 2006
• The Promise of Global Cervical-Cancer Prevention, Schiffman & Castle - New England Journal of Medicine, November 17, 2005
• Improving adolescent health: Focus on HPV vaccine acceptance, Zimet - Journal of Adolescent Health, 2005
• Vaccination as a prevention strategy for human papillomavirus related diseases, Kahn - Journal of Adolescent Health, 2005
• Understanding and preventing human papillomavirus infection during adolescence and young adulthood, editorial - Journal of Adolescent Health, 2005
• Impact of HPV infection in adolescent populations, Moscicki - Journal of Adolescent Health, 2005
• Cost-Effectiveness of Cervical-Cancer Screening in Five Developing Countries, Goldie et. al. - New England Journal of Medicine, November 17, 2005

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Meeting Reports and Documents

• Stop Cervical Cancer: Accelerating Global Access to HPV Vaccines - London, December 12-13, 2006
  - Advocacy, Information and Communication: Engaging Stakeholders at All Levels to Prepare for the Introduction of HPV Vaccines, Fisher and Bass
  - HPV Vaccines: Cost and Financing, Saxenian and Hecht
  - HPV Vaccines: Regulatory Issues, Brooke and Sherris
  - Assuring Access to Vaccines that Prevent Cervical Cancer, Pollack

• 'Partnering for HPV Vaccine Introduction' - report from PAHO-sponsored meeting in Washington, DC - October 5, 2005

News

• "Merck to Halt Lobbying for Vaccine for Girls" - New York Times, February 21, 2007
• "New Vaccine for Cervical Cancer Could Prove Useful in Men, Too" - New York Times, January 30, 2007
• India opens up to clinical trials of papillomavirus vaccines, Sharma - The Lancet, February 2006

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